KNOXVILLE, Tenn. (Sports Network) - LaMichael James ran for 134 yards and a touchdown and Darron Thomas threw for 202 yards and two scores to lead seventh-ranked Oregon to a 48-13 victory over Tennessee in the first-ever meeting between the two schools at Neyland Stadium.
James carried 16 times in his first action of the year after being suspended for the season opener, while Remene Alston, Jr added 40 yards and Thomas chipped in with 34 as the Ducks (2-0) churned out 245 yards on the ground to improve to 4-4 all-time against the SEC.
Thomas completed 17-of-32 passes in his second college start for the Ducks, who were runaway 72-0 winners in their opener over New Mexico State.
Tauren Poole carried 23 times for 162 yards and a score and Matt Simms completed 15-of-29 throws for 151 yards in a losing cause for the Volunteers (1-1), who are 14-14-3 against current members of the Pac-10.
Tennessee scored on the first possession of the game, driving 50 yards in seven plays and getting a 48-yard field goal from Daniel Lincoln to take the lead less than four minutes into the contest.
Oregon fumbled the ensuing kickoff and the Vols recovered at the Ducks 43-yard line. After the drive stalled at the 17, Lincoln came on to boot a 35-yard field goal to push the lead to 6-0.
Play was then delayed for 70 minutes with 8:53 left in the first quarter because of lightning in the area.
On their second possession after play resumed following the unanticipated break, the Ducks drove 51 yards on 13 plays and Rob Beard's 37-yard field goal cut the lead in half with just under 1 1/2 minutes left in the opening stanza.
The hosts responded by going 69 yards in five plays in just 1:59 to push the lead to 13-3 on a one-yard scoring run by Poole.
The Ducks took over with just under seven minutes left in the half and moved 60 yards in 13 plays and completed the drive with a 42-yard field goal from Beard that trimmed the lead to seven.
Tennessee went three and out on its next possession and punted back to the visitors, who moved quickly to tie the game.
Two Thomas completions brought the Ducks to the Vols 27 from where the sophomore completed a pass to David Paulson for the tying touchdown with just over one minute to go in the opening half.
Oregon took the lead for good just under five minutes into the third quarter on a highlight reel run by James, who started right, reversed his field, tightroped the left sideline, shed a tackle at the Vols 20 and made it to the end zone just as he was tripped up. The play was reviewed to see whether or not he had stepped out of bounds but stood as called on the field for a 72- yard score.
Tennessee advanced to the Ducks 27 before Cliff Harris picked off Simms in the right flat and weaved his way 76 yards to paydirt with just under 6 1/2 minutes left in the third to make it a 27-13 game.
"I was real disappointed from then on with how we competed," said Tennessee head coach Derek Dooley. "You would have thought we were down 40."
Oregon then put the game away with two touchdowns in the first 3 1/2 minutes of the final stanza.
Thomas's 30-yard scoring strike to Lavasier Tuinei finished off a six-play, 59-yard drive 1 1/2 minutes into the frame and a 79-yard punt return by Kenjon Barner removed any doubt about the outcome.
The Ducks added one final touchdown on a two-yard run by Alston with just under four minutes remaining in the game.